CLOSE

Specials

I agree We use cookies on this website to enhance your user experience. By clicking any link on this page you are giving your consent for us to set cookies. More info

Skip to: Curated Story Group 1
lifesciencesreview
US
EUROPE
APAC
CANADA
  • US
    • US
    • EUROPE
    • APAC
    • CANADA
    • LATAM
  • Home
  • Contributors
  • News
  • Conferences
  • Newsletter
  • Whitepapers
  • Magazine
×
#

Life Science Review Weekly Brief

Be first to read the latest tech news, Industry Leader's Insights, and CIO interviews of medium and large enterprises exclusively from Life Science Review

Subscribe

loading

Thank you for Subscribing to Life Science Review Weekly Brief

  • Home
  • News

Recommended picks

Advantages of Using Monoclonal Antibodies

Advantages of Using Monoclonal...

A Brief Overview Of Green Biotechnology Tools And Applications

A Brief Overview Of Green...

Key Advantages of Agtech in Farming

Key Advantages of Agtech in Farming

Nanotechnologys Impact on Environment: What to Know

Nanotechnologys Impact on...

How Automation in Pharmaceutical is Giving a New Direction to Drug Development

How Automation in Pharmaceutical is...

Ways Health Economics and Outcomes Research can Improve Decision Making Process

Ways Health Economics and Outcomes...

Top Agtech Industry Trends to Keep an Eye on

Top Agtech Industry Trends to Keep an...

Strategies to Mitigate Life Sciences Supply Chain Challenges

Strategies to Mitigate Life Sciences...

Advantages of Using Monoclonal Antibodies

Advantages of Using Monoclonal...

A Brief Overview Of Green Biotechnology Tools And Applications

A Brief Overview Of Green...

Key Advantages of Agtech in Farming

Key Advantages of Agtech in Farming

Nanotechnologys Impact on Environment: What to Know

Nanotechnologys Impact on...

How Automation in Pharmaceutical is Giving a New Direction to Drug Development

How Automation in Pharmaceutical is...

Ways Health Economics and Outcomes Research can Improve Decision Making Process

Ways Health Economics and Outcomes...

Top Agtech Industry Trends to Keep an Eye on

Top Agtech Industry Trends to Keep an...

Strategies to Mitigate Life Sciences Supply Chain Challenges

Strategies to Mitigate Life Sciences...

Opportunities Bioanalytics Holds for Pharma

Life Sciences Review | Thursday, December 10, 2020
Tweet

Bioanalysis is a progressive area for which the future holds exciting opportunities to improve sensitivity, accuracy, efficiency, data quality, assay throughput, data handling, analysis cost, and environmental impact.


FREMONT, CA: The advancement of the bioanalytical techniques brought a progressive discipline for which the future holds many opportunities to further innovation. The major impact of bioanalysis in the pharmaceutical industry is to get a quantitative measure of the drug and its metabolites. The purpose is to run the pharmacokinetics, toxicokinetics, bioequivalence, and exposure-response like pharmacokinetic studies.


Several bioanalytical techniques are performed in bioanalytical studies like hyphenated techniques, chromatographic techniques, and ligand binding assays. Here is more about the role of bioanalytical techniques and hyphenated instruments in evaluating the bioanalysis of the drugs.


Method of analysis is being continuously developed, enhanced, validated, collaboratively studied, and applied. Chromatographic separations are especially needed, which depend on the samples to be analyzed. The chromatographic procedure is essential for the systemic method to LC-MS/MS method development. In almost all cases, the desired separation can be attained easily with a few experiments. 


In other cases, considerable experimentation may be required.


Since many pharmaceutical compounds are polar, reverse phase chromatography is usually tried first in which non-polar stationery is utilized. The mobile phase includes water or buffer and an organic phase. Hence polar compounds get eluted first, and non-polar compounds are retained for a longer period. The stationary phases utilized in reverse phase chromatography are n-octadecyl, n-octyl, ethyl, phenyl, cyano, diol, and hydrophobic polymers. It is the first option for most samples, particularly neutral or un-ionized compounds that dissolve in water-organic compounds. The normal phase is tried if the reverse phase is not succeeded, where the sample may be strongly retained with complete acetonitrile as mobile phase.


Check Out: Top Pharma and Life Science Analytics Companies


A bioanalytical method involves procedures involved in collecting, processing, storage, and analyzing a biological matrix for a chemical compound. Bioanalytical method validation (BMV) is used to establish that a quantitative analytical method is suitable for biochemical applications. It covers the quantitative measurement of Xenobiotics of drugs.


Weekly Brief

loading
Towards a New World Order
> <
  • Regulatory Services 2023

    Top Vendors

    Current Issue
  • Clinical Lab Equipment 2023

    Top Vendors

    Current Issue
  • Regulatory Services 2023

    Top Vendors

    Current Issue
  • Clinical Lab Equipment 2023

    Top Vendors

    Current Issue

Read Also

Prophesying DNA Sequencing for 2023

Crucial Workflows of Next-Generation Sequencing

An Overview of Next-Generation Sequencing

The Role of AI in Accurate Medical Writing

Patrik Renblad to Join Cantargia as Chief Financial Officer

Overview of the Life Sciences BPO Market

Dr. Zamaneh Mikhak Joins TFF Pharmaceutical as the New Chief Medical Officer

The Significance of AI in Medical Writing

Loading...

Copyright © 2023 Life Sciences Review . All rights reserved. |  Subscribe |  About Us follow on linkedin

This content is copyright protected

However, if you would like to share the information in this article, you may use the link below:

https://www.lifesciencesreview.com/news/opportunities-bioanalytics-holds-for-pharma--nwid-206.html