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Biotech firms experienced a banner year in 2020. The COVID-19 pandemic highlighted the value of innovative medical solutions, leading to new opportunities for research, product approval, and funding.
Biotechnology in today's world plays a major role in varied disciplines. It is a broad domain which comprises of a bundle of technologies that operates the natural idle things into modified outcomes with its increased potential and sustainable return of products. The goals of biotechnology are endless, it is been employed for the benefit of humans and environment with corresponding development in scientific research and technological development.
Developing a new product or altering an existing one through biotechnologies encounters various difficulties. Designing and successfully getting out the desired product in laboratory level is the first level of accomplishment. Next is to produce the product in pilot scale and to analyze statistical study on the industrial framework. On successful yielding and fabrication of the bio-modified product and their aimed application depends on, forecasting and governing the challenges of biotechnology marketing.
While the pandemic increased the demand for biotech’s cutting-edge medical solutions, it also exacerbated a long-existing challenge for firms: sourcing and holding onto top talent.
Simply put, more firms seek highly-skilled life sciences professionals than there are qualified candidates. The sector became increasingly sophisticated in recent years, and biotech firms now seek employees with harder-to-find skills. More companies than ever incorporate artificial intelligence (AI) and process analytical technology (PAT) into their practices. As a result, firms seek professionals with expertise in engineering, data analytics, process development, and related emerging fields. The biotech boom in 2020 only furthered the problem, increasing the need for—but not the supply of—top talent.
Biotechnology is still in its infancy to find the answers of nature, understand the power beyond science, such as hydrogen and oxygen giving us water. Biotechnology has its own advantage and disadvantage Biotechnologists must be able to handle the society and address the controversial aspects of bringing a technology or a product in use.
We present to you, “Top 10 BioTech Startups – 2022.”
Commercializing a novel spatial biology tools platform— Deterministic Barcoding in Tissue for spatial-omics sequencing (DBiT-seq)—that provides researchers and clinicians with unprecedented multi-omics maps of gene expression of tissue sections
Concarlo's innovative and patented IpY, a novel therapeutic peptide, will be the first to address CDK2 resistance, the first to target p27, and the first to inhibit both CDK4 and CDK2 at the same time. Concarlo targets a specific cellular pathway to kill tumor cells rather than just slowing their proliferation. The company relies on the role of p27Kip1 — a vital "ON-OFF" switch that regulates the activities of major cancer-related proteins CDK4, CDK6, and CDK2.
Stacy Blain, Co-founder, & Chief Scientific Officer.Concarlo Therapeutics is a woman-founded and run organization that is working toward revolutionizing the metastatic breast cancer field," says Dr. Stacy Blain, the company's Co-founder, & Chief Scientific Officer
ConcarloTherapeutics
Management
Stacy Blain, Co-founder, & Chief Scientific Officer.
In 2016, Mary Gardner, the Founder and CEO,laid the foundation of DelNova. It is the only company in the industry that is developing a feasible solution, ReViVox™, to address botulinum toxin type A complications following aesthetic and medical neurotoxin therapies.Unlike others in the industry who have tried to resolve this issue by focusing on the toxin, DelNova addresses these complications ‘outside of the neuron.’ Its novel solution, ReViVox, acts as the perfect rescue product for all these complications without changing the toxin.DelNova is currently in the preclinical stage and is working toward collecting clinical data to validate the initial success of ReViVox. The company has already conducted a preliminary non-clinical proof of concept, collaborating with CRO partners to generate positive proof-of-concept data.
Gain Therapeutics is a preclinical biotechnology company focused on developing new medicines for protein misfolding diseases.
Gator Bio assists the R&D of therapeutic drugs with a best-in-class platform–Biolayer Interferometry (BLI)–that detects biomolecular interactions for rapid quantitation, kinetic measurements, epitope binning, and small molecule analysis. The BLI is a brilliant combination of engineering and sciences that results in revolutionary analytical technologies with superior performance and convenience at a fraction of the cost of traditional products.
Hong Tan, Founder and CEOThe Gator Prime and the Gator Plus platforms comprehensively meet the needs of all small and medium biotech companies who are developing different therapeutics or biologics
Developing gene therapies, antibodies, and regenerative platforms for treatment of cancer, malaria, and other diseases.
Ibex Biosciences
Management
Norman Lai, CTO, Vidal de la Cruz, CSO & Co-CEO, A. Murat Croci, Co-Founder & Co-CEO, Saule Dairabayeva, Markets Manager, Michael J. Karlin, Co-Founder & CBO
Kineta is a Seattle-based clinical-stage biotechnology company that sets itself on a mission to develop next-gen immunotherapies that transform patients’ lives. The company leverages its longstanding experience in immunology and in-depth expertise in innate immunity to develop first-in-class immunotherapies that address the challenges pertaining to current cancer therapies. By developing immuno-oncology drugs that use the body's innate immune system to fight cancer, they aim to improve the overall and long-term survival of cancer patients.
Leukocare is a leading provider of bioinformatics based drug product formulation and development of technologies for the biological functionalization of medical devices, as well as the stabilization and protection of proteins. Leukocare stepped into the biopharmaceutical sector as a product development company almost 20 years ago;. It pioneered the development of a coating for filter membrane, employing an antibody to reduce the activity of neutrophil granulocytes.
Michael Scholl, CEOWe are highly specialized in stabilizing all kinds of biological molecules. And we have a very strong bioinformatics based approach which we apply to different project resulting in an optimized formulation using less drug substance in less times
MAIA Biotechnology is a targeted therapy immune-oncology company focused on developing and commercializing first-in-class drugs with novel mechanisms of action.
MOBILion Systems’ structures for lossless ion manipulation (SLIM) technology provides unprecedented capability to separate clinically relevant molecules for MS analysis. It helps researchers drastically improve metabolic disease, drug, and biomarker discovery, paving the way for earlier disease detection, more accurate diagnostics, and reduced healthcare costs. More importantly, SLIM provides a very long, 13 meter path length to allow for maximum ion separation. As a result, researchers can use the arrival time as a fourth dimension of separation to accurately resolve isomers.
MOBILION SYSTEMS
Management
Julie Sperry, Senior Vice President Biopharma Business