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Predicting the future of any scientific discipline is almost impossible, especially for one as young as bioinformatics, but in my view the future of biology will increasingly be shaped by the interplay of bioinformatics and ‘classical’ biology. Currently, the field is undergoing an enormous expansion, as witnessed by the astonishing increase in the number of advertisements for bioinformatics personnel during the past year.
Bioinformatics is an interesting combination of biology and computational sciences, which help scientists and researchers to do more biological experiments to improve the life of living being. Gene expression is fundamental biological basics of cell biology. It is also responsible for genetic as well as physical or biochemical characteristics of an organism.
The study of gene expression analysis helps to predict resultant protein product, in identifying abnormal functioning of cells which may responsible for various diseases, and in designing new drugs. For analysis purpose, DNA Microarray is an important tool as number of genes can simultaneously be observed.
The output of DNA Microarray is vast databases which need to be processed by computation tools to take out biological significance. Computation tools include various algorithms of data mining, pattern recognition, support vector machines etc. Vast literature is available which demonstrate different algorithms and their result for analysis purpose.
The evolution of bioinformatics, which started with sequence analysis and has led to high-throughput whole genome or transcriptome annotation today, is now going to be directed towards recently emerging areas of integrative and translational genomics, and ultimately personalized medicine. Therefore considerable efforts are required to provide the necessary infrastructure for high-performance computing, sophisticated algorithms, advanced data management capabilities, and-most importantly-well trained and educated personnel to design, maintain and use these environments.
This edition outlines the most promising trends in bioinformatics, which may play a major role in the pursuit of future biological discoveries and medical applications.
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Analome is dedicated to accelerating scientific discovery with experienced bioinformatics, their experience allows them to develop and provide informatics solutions for virtually any project in the omic-sciences. They form collaborative partnerships with scientists to help them move quickly from ideas, to experiments, to data, to knowledge
Kognitic’s trial intelligence platform for oncology automates in entirety the bioinformatics associated with clinical trials. The solution is powered by NLP algorithms that can normalize and assess the latest clinical trial, drug, and financial data from various sources daily
Jaseem Mahmmdla, Co-Founder and CTO, Gayathri Raghupathy, VP Scientific Affairs and StrategyKognitic helps trials attain the data-driven edge on biomarker strategy, patient segmentation, study design, site analysis, and patient recruitment
Kognitic
Management
Jaseem Mahmmdla, Co-Founder and CTO, Gayathri Raghupathy, VP Scientific Affairs and Strategy
Aqil Ahsan, Founder and CEO
BioInformatics is the leading research and advisory firm serving the life science and diagnostic industries. Their expertise includes primary quantitative and qualitative research in addition to secondary research and published reports. They are a full-service firm utilizing both “bottom-up” and “top down” research methodologies.
Brendan Bioanalytics develops advanced analysis and workflow software for potency bioassays, immunoassays, and immunogenicity assays.Their STATLIA software developed and introduced the Gold Standard 5 parameter and 4 parameter logistic models for nonlinear curve fitting.
DNASTAR is a global software company that has been meeting the needs of life scientists for over 30 years by providing innovative and easy-to-use desktop software tools for today's life scientists. DNASTAR Lasergene provides all the software clients need for molecular biology, genomics, and structural biology research and is available as a complete package or as individual suites
Founded in 2003, Geneious' mission is to create bioinformatics solutions for the analysis, interpretation, and application of molecular sequence data. They aim to help scientists in biology and medicine to work directly with DNA data. Geneious Prime and Geneious Biologics take away the pain of data management and computational complexity, allowing scientists to focus on their research
Golden Helix has been delivering industry-leading bioinformatics solutions for the advancement of life science research and translational medicine for over 20 years. Their innovative technologies and analytic services empower scientists and healthcare professionals at all levels to derive meaning from the rapidly increasing volumes of genomic data produced from microarrays and next-generation sequencing
Illumina is an innovative technology and revolutionary assays aiming the analyze genetic variation and function. As a company that places a high value on collaborative interactions, rapid delivery of solutions, and prioritizing the needs of its customers, they strive to meet this challenge
M2GEN® is an oncology-focused health informatics solutions company with the mission to help patients get access to the best treatments by leveraging clinical and molecular data to accelerate the discovery, development and delivery of tailored and more personalized therapies
QIAGEN is the leading global provider of Sample to Insight solutions that enable customers to gain valuable molecular insights from samples containing the building blocks of life. Bioinformatics software and knowledge bases interpret data to report relevant, actionable insights. Automation solutions tie these together in seamless and cost-effective workflows