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What are Some Popular Applications of Analytical Testing Techniques?

Life Sciences Review | Thursday, June 17, 2021
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Analytical procedures are essential to equivalence and risk assessment, management. It helps establish product-specific acceptance criteria and results in stability.


FREMONT, CA: Analytical testing, also called material testing, is a broad term used to describe various techniques used to identify a particular sample's chemical makeup or characteristics. Manufacturers in pharmaceuticals, food, electronics, and plastics often use analytical testing to analyse reverse engineering or failure and identify contaminants or stains on products. Below are some applications of analytical testing techniques.


Auger Electron Spectroscopy (AES)


Auger Electron Spectroscopy is a technique used to obtain information on material or sample surfaces and interfaces. AES is an excellent tool for recognising contaminants or stains on conductive and semi-conductive surfaces, analysing passivation layers on medical devices, and analysing small features such as particles, small diameter wires, or electronic bonding pads.


Electron Spectroscopy for Chemical Analysis (ESCA)


Electron Spectroscopy for Chemical Analysis is a strategy used to obtain essential, binding information about a material or sample's surfaces and interfaces. ESCA is used to identify contamination, stainless steel passivation, chromium, and iron oxidation and study surface chemistry of polymers, glasses, and other insulators.


Liquid Particle Counting (LPC)


Liquid Particle Counting is an instrument used to detect particle size and distribution in liquid or solid samples. Particles are retrieved with water, then analysed by laser diode irradiating the liquid and detecting the dispersed light. LPC is used to determine particle size and distribution on hard drives, magnetic tapes, medical devices, combustion, and hydraulic fluid particles. It is also used to determine particle size in colloidal solutions and inks.


Light Microscopy & Imaging


Light Microscopy & Imaging, or Reflected Light Microscopy, creates a magnified sample image. The magnified image is obtained by light diversion by combining lenses. Light Microscopy and Imaging leverage to study the structure and surface of various patterns, including polymers, plastics, glass, wafers, and integrated circuits, ceramics, and many other materials.


Ion Chromatography (IC)


Ion chromatography is a method that uses high-performance liquid chromatography and conductivity detector to separate and quantify anions and cations. IC is especially useful in clinical devices, electronics, and plastics manufacturings as it can disclose microscopic ionic contamination that can cause product malfunction, failure, or safety issues.


Thermal Gravimetric Analysis (TGA)


Thermal Gravimetric Analysis is an instrument used to detect weight loss in a controlled environment. TGA is often used to evaluate polymer differences and the amount of organic and inorganic filler used in polymers.


Melt Flow Rate


Melt Flow Rate is a method for measuring polymer viscosity at a constant temperature through a defined orifice. Melt Flow Rate is often used to detect lot-to-lot variations and polymer degradation caused by processing; this is especially useful for plastic compounds.


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